Generic Name: Japanese encephalitis virus vaccine (SA14-14-2)
Brand Names: Ixiaro
What is Japanese encephalitis virus vaccine (SA14-14-2)?
Japanese encephalitis is a serious disease caused by a virus. It is the leading cause of viral encephalitis (inflammation of the brain) in Asia. Encephalitis is an infection of the membrane around the brain and spinal cord. This infection often causes only mild symptoms, but prolonged swelling of the brain can cause permanent brain damage or death.
Japanese encephalitis virus is carried and spread by mosquitos.
The Japanese encephalitis SA14-14-2 vaccine is used to help prevent this disease in adults and adolescents who are at least 17 years old.
This vaccine works by exposing you to a small dose of the virus, which causes the body to develop immunity to the disease. This vaccine will not treat an active infection that has already developed in the body.
This vaccine is recommended for people who live in or travel to areas where Japanese encephalitis is known to exist, or where an epidemic has recently occurred.
You should receive the vaccine and booster dose at least 1 week prior to your arrival in an area where you may be exposed to the virus.
Not everyone who travels to Asia needs to receive a Japanese encephalitis vaccine. Follow your doctor instructions or the recommendations of the Centers for Disease Control and Prevention (CDC).
This vaccine is also recommended for people who work in a research laboratory and may be exposed to Japanese encephalitis virus through needle-stick accidents or inhalation of viral droplets in the air.
Like any vaccine, the Japanese encephalitis SA14-14-2 vaccine may not provide protection from disease in every person.
What is the most important information I should know about this vaccine?
The Japanese encephalitis SA14-14-2 vaccine is given in a series of 2 shots. The shots are usually 28 days apart. Your individual booster schedule may be different from these guidelines. Follow your doctor's instructions or the schedule recommended by the health department of the state you live in.
Japanese encephalitis SA14-14-2 vaccine is for use in adults and adolescents who are at least 17 years old.
This vaccine is recommended for people who live in or travel to areas where Japanese encephalitis is known to exist, or where an epidemic has recently occurred.
You should receive the vaccine and booster dose at least 1 week prior to your arrival in an area where you may be exposed to the virus.
This vaccine is also recommended for people who work in a research laboratory and may be exposed to Japanese encephalitis virus through needle-stick accidents or inhalation of viral droplets in the air.
Becoming infected with Japanese encephalitis is much more dangerous to your health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.
What should I discuss with my healthcare provider before receiving this vaccine?
You should not receive this vaccine if you have ever had a life-threatening allergic reaction to a Japanese encephalitis vaccine.
Before receiving this vaccine, tell the doctor if you are allergic to any foods or drugs, or if you have:
a bleeding or blood clotting disorder;
a weak immune system caused by disease such as HIV or AIDS, bone marrow transplant, or by using certain medicines or receiving cancer treatments.
You can still receive a vaccine if you have a cold or low fever. In the case of a more severe illness with a high fever (more than 100 degrees) or any type of infection, wait until you get better before receiving this vaccine.
Vaccines may be harmful to an unborn baby and generally should not be given to a pregnant woman. However, not vaccinating the mother could be more harmful to the baby if the mother becomes infected with a disease that this vaccine could prevent. Your doctor will decide whether you should receive this vaccine, especially if you have a high risk of infection with the Japanese encephalitis virus. It is not known whether Japanese encephalitis vaccine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How is this vaccine given?
This vaccine is given as an injection (shot) into a muscle of your upper arm. You will receive this injection in a doctor's office or other clinic setting.
The Japanese encephalitis SA14-14-2 vaccine is given in a series of 2 shots. The shots are usually 28 days apart. Your individual booster schedule may be different from these guidelines. Follow your doctor's instructions or the schedule recommended by the health department of the state you live in.
In addition to receiving the Japanese encephalitis vaccine, use protective clothing, insect repellents, and mosquito netting around your bed to further prevent mosquito bites that could infect you with the Japanese encephalitis virus.
What happens if I miss a dose?
Contact your doctor if you will miss a booster dose or if you get behind schedule. The next dose should be given as soon as possible. There is no need to start over.
Be sure you receive all recommended doses of this vaccine. If you do not receive the full series of vaccines, you may not be fully protected against the disease.
What happens if I overdose?
An overdose of this vaccine is unlikely to occur.
What should I avoid before or after receiving this vaccine?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
This vaccine side effects
You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first shot. Keep track of any and all side effects you have after receiving this vaccine. When you receive a booster dose, you will need to tell the doctor if the previous shots caused any side effects.
Becoming infected with Japanese encephalitis is much more dangerous to your health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; dizziness, weakness, fast heart rate; swelling of your face, lips, tongue, or throat.
Less serious side may include:
headache, tired feeling;
muscle pain, back pain;
low fever, chills, flu symptoms;
cold symptoms such as stuffy nose, sneezing, sore throat, cough;
mild itching or skin rash.
nausea, diarrhea; or
pain, redness, tenderness, or a hard lump where the shot was given.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Japanese encephalitis virus vaccine Dosing Information
Usual Adult Dose for Japanese Encephalitis Virus Prophylaxis:
0.5 mL intramuscularly into the deltoid muscle on days 0 and 28. Immunization series should be completed at least 1 week prior to potential exposure to Japanese encephalitis virus.
Usual Pediatric Dose for Japanese Encephalitis Virus Prophylaxis:
17 years or older:
0.5 mL intramuscularly into the deltoid muscle on days 0 and 28. Immunization series should be completed at least 1 week prior to potential exposure to Japanese encephalitis virus.
What other drugs will affect Japanese encephalitis virus vaccine (SA14-14-2)?
Before receiving this vaccine, tell the doctor about all other vaccines you have recently received.
Also tell the doctor if you have recently received drugs or treatments that can weaken the immune system, including:
an oral, nasal, inhaled, or injectable steroid medicine;
medications to treat psoriasis, rheumatoid arthritis, or other autoimmune disorders, such as azathioprine (Imuran), efalizumab (Raptiva), etanercept (Enbrel), leflunomide (Arava), and others; or
medicines to treat or prevent organ transplant rejection, such as basiliximab (Simulect), cyclosporine (Sandimmune, Neoral, Gengraf), muromonab-CD3 (Orthoclone), mycophenolate mofetil (CellCept), sirolimus (Rapamune), or tacrolimus (Prograf).
This list is not complete and there may be other drugs that can affect Japanese encephalitis vaccine. Tell your doctor about all the prescription and over-the-counter medications you have received. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
More Japanese encephalitis virus vaccine resources
- Japanese encephalitis virus vaccine Use in Pregnancy & Breastfeeding
- Japanese encephalitis virus vaccine Drug Interactions
- Japanese encephalitis virus vaccine Support Group
- 0 Reviews for Japanese encephalitis virus vaccine - Add your own review/rating
- Ixiaro Advanced Consumer (Micromedex) - Includes Dosage Information
- Ixiaro Consumer Overview
Compare Japanese encephalitis virus vaccine with other medications
- Japanese Encephalitis Virus Prophylaxis
Where can I get more information?
- Your doctor or pharmacist may have information about this vaccine written for health professionals that you may read. You may also find additional information from your local health department or the Centers for Disease Control and Prevention.
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